Premature ovarian failure - Renew Hormone Clinic

Premature Ovarian Failure (POF)

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition where the ovaries stop functioning normally before age 40. This results in irregular periods or missed periods altogether along with:

• Reduced fertility and difficulties getting pregnant
• Menopausal symptoms like hot flashes, vaginal dryness, and mood changes

Some key points about POF:

• It impacts 1 out of 100 women by age 40
• The causes are often unknown but can include:
  • Genetic factors - chromosomal abnormalities or familial inheritance
  • Autoimmune disease damaging the ovaries
  • Cancer treatment like radiation/chemotherapy
  • Infections or pelvic surgery
• Diagnosis involves blood tests to measure hormone levels (FSH, estradiol) which are abnormally high when ovarian function declines
• Treatment focuses on managing symptoms:
  • Hormone therapy with estrogen/progesterone to regulate cycles
  • Fertility drugs or egg freezing if pregnancy is desired
  • Lifestyle changes like stress reduction
• Long term health risks include earlier risk of osteoporosis and heart disease without hormone therapy

While upsetting, a POF diagnosis does not necessarily mean a woman can't get pregnant. Some still ovulate intermittently or respond to fertility treatment. Working closely with both a gynecologist and fertility specialist at Renew Hormone Clinic offers the best chance of success.

Support groups and counseling can also help women adjust emotionally to the life changes POF involves. Proactive health maintenance gives the best odds of coping well. Though challenging, living fully with POF is certainly possible.

The key is getting proper medical care for both physical and emotional aspects. Advancements in fertility treatment along with better understanding of POF offer hope for better management.